Sugar acids and derivatives
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 1 MG
Glucuronic acid sodium is a polysaccharide that exhibits anti-inflammatory activity, supporting the healing of ulcerative colitis. It also enhances the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin. Additionally, it modulates gut microbiota by increasing beneficial bacterial populations while suppressing harmful ones.
- Exhibits anti-inflammatory activity
- Supports healing of ulcerative colitis
- Enhances intestinal barrier function
- Modulates gut microbiota
- Increases beneficial bacterial populations
- Suppresses harmful bacterial populations
Medchemexpress LLC D-Thyroxine | 51-49-0 | 98.0% | C15H11I4NO4 | 25 MG
D-Thyroxine (D-T4) is an orally active thyroid hormone that inhibits the secretion of TSH. It can inhibit goiter, promote metamorphosis of tadpoles, and influence cholesterol metabolism. D-Thyroxine can be used for the study of hypercholesterolemia. This product is intended for research applications only.
- Orally active thyroid hormone
- Inhibits the secretion of TSH
- Can inhibit goiter
- Promotes metamorphosis of tadpoles
- Influences cholesterol metabolism
- Used for the study of hypercholesterolemia
Medchemexpress LLC 4-Methylumbelliferyl-β-D-xylopyranoside | 6734-33-4 | 99.7% | 308.29 | 50 MG
4-Methylumbelliferyl-β-D-xylopyranoside (MuX) can be used as a substrate for researching β-Xylosidase activity. It exhibits burst, steady-state kinetics, supporting the conclusion that the hydrolysis of glycosidic bonds for this substrate is rapid. This product is for research use only and not sold to patients.
- Purity of 99.7%
- Initial source is animal
- Structure classification: Phenylpropanoids, Coumarins
- Used as a substrate for β-Xylosidase activity research
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Mac glucuronide linker-1 | 2222981-71-5 | 96.4% | 897.90 g/mol | C42H47N3O17S | 1 G
MAC glucuronide linker-1 is a glycosidase-cleavable antibody-drug conjugate (ADC) linker supplied as a purified small molecule for research use. It incorporates a glucuronide cleavable moiety to enable enzymatic release of attached payloads, and is provided at high purity for synthesis and conjugation workflows.
- Glycosidase-cleavable glucuronide linker enabling enzymatic payload release.
- Molecular weight approximately 897.90 g/mol.
- Molecular formula C42H47N3O17S.
- High purity (96.4%) suitable for research applications.
- Available in multiple sizes including a 1 G package.
- For research use only; not for human therapeutic use.
Medchemexpress LLC D-Glucuronic acid sodium salt monohydrate | 207300-70-7 | 10 G
D-Glucuronic acid sodium salt monohydrate is a primary component of several anti-inflammatory proteoglycans, which can foster embryonic development and hinder cell aggregation. When metabolized into ethyl glucuronide, it activates Toll-like receptor 4 (TLR4), leading to pain. This compound and its derivative, glucurono-lactone, can act as liver detoxifiers for human health prevention, with its derivatives also exhibiting anti-tumor activity.
- Purity: 98.0%
- Molecular weight: 234.14
- Formula: C6H11NaO8
- Appearance: Solid, white to off-white
- Acts as a component of anti-inflammatory proteoglycans
- Promotes early embryonic development
- Inhibits cell aggregation
- Functions as a liver detoxifier
- Derivatives show anti-tumor activity
- Activates Toll-like receptor 4 (TLR4) when metabolized
- Categorized as a ketone, aldehyde, and acid
Medchemexpress LLC 4-Methylumbelliferyl β-D-galactopyranoside | 6160-78-7 | MFCD00036773 | 99.1% | 338.31 | 500 MG
4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase. When cleaved, it produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer.
- Fluorescent substrate for β-galactosidase
- Produces a water-soluble blue fluorescent coumarin fluorophore when cleaved
- Detectable using a fluoroenzymeter or fluorometer
- White to off-white solid
- Molecular weight of 338.31
- Purity of 99.06%
- Excitation at 390 nm
- Emission at 480 nm
Medchemexpress LLC D-Glucuronic acid sodium monohydrate-13C6 | 207300-70-7 | 5 MG
D-Glucuronic acid sodium monohydrate-13C6 is the 13C-labeled version of D-Glucuronic acid sodium salt monohydrate. D-Glucuronic acid sodium salt monohydrate is an endogenous metabolite.
- Product type: Stable isotope
- Purity: 99.9%
- Molecular weight: 240.09
- Formula: 13C6H11NaO8
- Appearance: Solid
- Color: White to off-white
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes of hydrogen, carbon, and other elements are used as tracers for drug development
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs
- Storage (powder): -20°C for 3 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- For research use only
- Documentation: Data Sheet, COA, SDS, handling instructions available
Medchemexpress LLC UDP-3-O-acyl-GlcNAc | 108636-29-9 | 1 MG
UDP-3-O-acyl-GlcNAc is an E. coli metabolite involved in the 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway. It has a molecular weight of 833.71 and a chemical formula of C31H53N3O19P2. This product is for research use only.
- Molecular weight: 833.71
- Formula: C31H53N3O19P2
- Initial source: Microorganisms (Escherichia)
- For research use only
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 50 MG
Glucuronic acid sodium is a polysaccharide that shows anti-inflammatory activity, helps heal ulcerative colitis, and improves the intestinal barrier by increasing tight junction proteins like ZO-1 and Occludin. It also modifies gut microbiota by increasing beneficial bacteria and suppressing harmful ones.
- Shows anti-inflammatory activity
- Helps heal ulcerative colitis
- Improves intestinal barrier by increasing tight junction proteins like ZO-1 and Occludin
- Modifies gut microbiota by increasing beneficial bacteria and suppressing harmful ones
Medchemexpress LLC Prosaikogenin D | 103629-72-7 | 10 MG
Prosaikogenin D is isolated from the roots of Buleurum bicaule Helm (Apiaceae) and exhibits anti-cancer activity.
- Suppresses the proliferation of A549 cells with an IC50 of 57.2 μg/mL.
Medchemexpress LLC 4-Methylumbelliferyl-α-D-Glucopyranoside | 17833-43-1 | 99.99% | 338.31 | 1 ML
4-Methylumbelliferyl-α-D-Glucopyranoside is a fluorescent substrate for α-glucosidase. Upon cleavage, it releases the fluorescent moiety 4-methylumbelliferyl (4-MU), which exhibits pH-dependent fluorescence excitation activity. Excitation wavelengths are 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3), with emission wavelengths ranging from 445-455 nm as pH decreases.
- Used as a biomarker to quantify α-glucosidase activity in infant blood spot samples for Fabry and Pompe diseases.
- Intended for research use only.
- Not sold to patients.
Medchemexpress LLC Beta-D-glucuronide-pNP-carbonate | 894095-98-8 | MFCD31715405 | >96.0% | 913.83 g/mol | C45H43N3O18 | 50 MG
β-D-glucuronide-pNP-carbonate is a glycosidase-cleavable antibody-drug conjugate (ADC) linker that contains a para-nitrophenyl carbonate reactive handle and a β-D-glucuronide cleavable trigger. It is supplied as a solid for research use and is designed to release payloads upon enzymatic cleavage by glucuronidase.
- Glycosidase-cleavable linker for targeted payload release.
- Para-nitrophenyl carbonate reactive handle for payload attachment.
- Solid form suitable for standard laboratory handling.
- Available in small research-scale quantities for synthesis work.
- Intended for research use only; not for clinical or human use.